Description

Methyl 5-(Methylsulfonyl)-1H-Indole-2-Carboxylate is a high-value, functionalized indole derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the strategic combination of an electron-withdrawing methylsulfonyl group and a versatile methyl ester, making it an essential building block for constructing complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of biologically active indole-based compounds, including potential kinase inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the indole scaffold.
• Material Science: Serves as a monomer or functional unit in the creation of specialty polymers and organic electronic materials.
• Chemical Synthesis: Employed in cross-coupling reactions, cyclizations, and as a substrate for further functionalization to create diverse chemical libraries.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis and medicinal chemistry research programs.

Basic Information

Product Name	Methyl 5-(Methylsulfonyl)-1H-Indole-2-Carboxylate
CAS No.	205873-28-5
Molecular Formula	C11H11NO4S
Molecular Weight	253.27 g/mol
Synonyms	5-(Methylsulfonyl)-1H-indole-2-carboxylic acid methyl ester; Methyl 5-(methylsulfonyl)indole-2-carboxylate; 1H-Indole-2-carboxylic acid, 5-(methylsulfonyl)-, methyl ester; 2-Carbomethoxy-5-methylsulfonylindole; 5-Methanesulfonyl-1H-indole-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-(Methylsulfonyl)-1H-Indole-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.