Description

1,2,8-Indolizinetriol, Octahydro-6-(Hydroxymethyl)-5-Methyl-, [1S-(1Alpha,2Alpha,5Ba,6Ba,8Ba,8Aba)]- (9Ci) is a complex, stereochemically defined indolizine derivative with multiple hydroxyl functionalities, making it a valuable chiral building block for advanced organic synthesis. Its precise stereochemistry and functional group array are critical for applications requiring high specificity and purity, particularly in pharmaceutical research and development. This compound is primarily targeted at R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients or complex natural product analogs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for complex molecules with defined stereocenters.
• Agrochemical Research: Used in the synthesis of novel, biologically active compounds for crop protection and pest management.
• Fine Chemical Synthesis: Acts as a versatile building block for creating complex natural product analogs and specialty chemicals.
• Academic & Institutional Research: Employed in universities and research institutes for methodological studies in asymmetric synthesis and medicinal chemistry.
• Process Chemistry Development: Utilized for scaling up synthetic routes and optimizing manufacturing processes for target molecules.
• Bioconjugate Chemistry: Potential use in the development of antibody-drug conjugates (ADCs) or other targeted therapeutics due to its functional handles.

Basic Information

Product Name	1,2,8-Indolizinetriol, Octahydro-6-(Hydroxymethyl)-5-Methyl-, [1S-(1Alpha,2Alpha,5Ba,6Ba,8Ba,8Aba)]- (9Ci)
CAS No.	205868-14-0
Molecular Formula	C11H21NO4
Molecular Weight	231.29 g/mol
Synonyms	(1S,2S,5R,6R,8R,8aR)-Octahydro-6-(hydroxymethyl)-5-methylindolizine-1,2,8-triol; (1S,2S,5R,6R,8R,8aR)-5-Methyloctahydro-6-(hydroxymethyl)indolizine-1,2,8-triol; 1,2,8-Indolizinetriol, octahydro-6-(hydroxymethyl)-5-methyl-, (1S,2S,5R,6R,8R,8aR)-; Swainsonine derivative; Indolizidine triol derivative
EINECS	Contact for details

Quality Control

Our 1,2,8-Indolizinetriol derivative is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.