Description

Dl-Phenylalanine-D11 CAS NO 205829-16-9 is a stable isotope-labeled analog of the essential amino acid phenylalanine, where eleven hydrogen atoms are replaced by deuterium. This high-purity compound is critical for advanced research and analytical applications requiring precise molecular tracking and quantification. It is primarily utilized by scientists and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors for applications such as metabolic studies, internal standards for mass spectrometry, and drug development.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a crucial reference compound in quantitative LC-MS and GC-MS analysis for accurate measurement of endogenous phenylalanine levels in biological samples.
• Metabolic Pathway Research: Used as a tracer in pharmacokinetic (PK) and pharmacodynamic (PD) studies to investigate amino acid metabolism, protein synthesis, and related disorders.
• Pharmaceutical Development: Employed in the synthesis and testing of deuterated drug candidates to study their absorption, distribution, metabolism, and excretion (ADME) profiles.
• Nutritional and Clinical Research: Facilitates studies on phenylketonuria (PKU) and other metabolic conditions by enabling precise tracking of phenylalanine utilization.
• NMR Spectroscopy: Acts as a valuable tool in nuclear magnetic resonance (NMR) spectroscopy for structural elucidation and dynamic studies of biomolecules.
• Biochemical Reagent: Used in enzymatic assays and as a component in specialized cell culture media for controlled experimental conditions.

Basic Information

Item	Detail
Product Name	Dl-Phenylalanine-D11
CAS No.	205829-16-9
Molecular Formula	C9H2D11NO2
Molecular Weight	~187.27 g/mol
Synonyms	DL-Phenylalanine-d11; (RS)-2-Amino-3-phenylpropionic acid-d11; Phenylalanine-d11 (racemic); Deuterated DL-Phenylalanine; 2-Amino-3-phenylpropanoic-2,3,3-d3,ring-d5,α-d3 acid; Phenylalanine (ring-d5, 2,3,3-d3, α-d3); UNII-9K628S5C2P; DL-α-Amino-β-phenylpropionic acid-d11
EINECS	Contact for details

Quality Control

Our Dl-Phenylalanine-D11 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and MS, to confirm chemical identity, isotopic purity (deuterium enrichment), and chemical purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical specifications. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccants or storage under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98 atom % D
Chemical Purity	≥ 95% (by NMR)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.