Description

2H-Cyclopenta[B]Furan-2-One, 3,3A,4,6A-Tetrahydro-3-(Hydroxymethylene)-, (3Z,3Aalpha,6Aalpha)- (9Ci) is a high-value, advanced pharmaceutical intermediate characterized by its complex fused-ring structure and hydroxymethylene functional group. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in developing new drug candidates and complex organic molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of proprietary drug substances and novel chemical entities.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex polycyclic frameworks and exploring new reaction pathways.
• Agrochemical Development: Potential intermediate in the research and synthesis of advanced, high-performance crop protection agents.
• Material Science Precursor: Investigated for the development of specialty polymers or organic electronic materials due to its unique fused-ring system.
• Asymmetric Catalysis Studies: Employed as a substrate or ligand precursor in the development of stereoselective catalytic processes.

Basic Information

Product Name	2H-Cyclopenta[B]Furan-2-One, 3,3A,4,6A-Tetrahydro-3-(Hydroxymethylene)-, (3Z,3Aalpha,6Aalpha)- (9Ci)
CAS No.	205815-42-5
Molecular Formula	C8H8O3
Molecular Weight	152.15 g/mol
Synonyms	3-(Hydroxymethylene)-3a,4,6,6a-tetrahydro-2H-cyclopenta[b]furan-2-one; (3Z,3aα,6aα)-3-(Hydroxymethylene)hexahydro-2H-cyclopenta[b]furan-2-one; 3-(Hydroxymethylene)-3a,4,6,6a-tetrahydro-2H-cyclopenta[b]furan-2-one (9CI); 205815-42-5; 3-(Hydroxymethylene)hexahydro-2H-cyclopenta[b]furan-2-one; Tetrahydro-3-(hydroxymethylene)-2H-cyclopenta[b]furan-2-one
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical techniques including HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support development and commercial projects with specifications that can meet GMP standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.