Description

Cyclopropanemethanol, 2-(4-Ethoxyphenyl)-Alpha,α-Dimethyl-, (1R,2R)-Rel- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals requiring precise stereochemistry. It is primarily needed by research and development laboratories, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate complex, functionalized cyclopropane motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and production of novel therapeutic agents, particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the cyclopropane structure confers specific biological activity.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in studies exploring new catalytic methodologies for stereoselective synthesis.
• Material Science Precursor: Potential application in the synthesis of specialized monomers for polymers with unique thermal or mechanical properties.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	Cyclopropanemethanol, 2-(4-Ethoxyphenyl)-Alpha,α-Dimethyl-, (1R,2R)-Rel- (9Ci)
CAS No.	205674-81-3
Molecular Formula	C14H20O2
Molecular Weight	220.31 g/mol
Synonyms	(1R,2R)-rel-2-(4-Ethoxyphenyl)-α,α-dimethylcyclopropanemethanol; (1R,2R)-2-(4-Ethoxyphenyl)-1,1-dimethylcyclopropanemethanol; rel-(1R,2R)-2-(4-Ethoxyphenyl)-1,1-dimethylcyclopropanemethanol; 2-(4-Ethoxyphenyl)-1,1-dimethylcyclopropanemethanol, (1R,2R)-rel-; Cyclopropanemethanol, 2-(4-ethoxyphenyl)-α,α-dimethyl-, (1R,2R)-rel-; Chiral Cyclopropane Methanol Derivative; 205674-81-3
EINECS	Contact for details

Quality Control

Our production of Cyclopropanemethanol, 2-(4-Ethoxyphenyl)-Alpha,α-Dimethyl-, (1R,2R)-Rel- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot undergoes comprehensive analytical characterization, including chiral HPLC for enantiomeric excess determination and NMR for structural confirmation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.