Description

3-Endo-Hydroxymethylbicyclo[2.2.1]Hept-5-Enyl-2-Endo-Amine, Hydrochloride, 97 is a high-purity, chiral bicyclic amine hydrochloride salt, a critical building block in advanced organic synthesis. Its value lies in its rigid, functionalized norbornene skeleton, which is essential for constructing complex molecular architectures with precise stereochemistry. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for applications in medicinal chemistry, asymmetric catalysis, and the development of novel polymers and materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in neurology and antiviral therapies.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands and organocatalysts used in enantioselective synthesis.
• Advanced Material Science: Building block for synthesizing specialty polymers, dendrimers, and liquid crystals with unique thermal and mechanical properties.
• Agrochemical Research: Intermediate in the development of novel, high-efficacy crop protection agents with specific stereochemical requirements.
• Academic & Industrial R&D: Used in methodological studies and exploration of new reaction pathways in organic chemistry.

Basic Information

Product Name	3-Endo-Hydroxymethylbicyclo[2.2.1]Hept-5-Enyl-2-Endo-Amine, Hydrochloride, 97
CAS No.	205639-90-3
Molecular Formula	C9H16ClNO
Molecular Weight	189.68 g/mol
Synonyms	2-Amino-3-(hydroxymethyl)bicyclo[2.2.1]hept-5-ene hydrochloride; (1R,2R,3S,4S)-3-(Aminomethyl)bicyclo[2.2.1]hept-5-ene-2-methanol hydrochloride; endo-2-Amino-3-(hydroxymethyl)-2-norbornene hydrochloride; Bicyclo[2.2.1]hept-5-ene-2-methanol, 3-(aminomethyl)-, hydrochloride, (1R,2R,3S,4S)-; 3-(Aminomethyl)-5-norbornene-2-methanol hydrochloride; Norbornene amine hydrochloride derivative
EINECS	Contact for details

Quality Control

Our 3-Endo-Hydroxymethylbicyclo[2.2.1]Hept-5-Enyl-2-Endo-Amine, Hydrochloride, 97 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the specified purity and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.