Description

3-Endo-Hydroxymethylbicyclo[2.2.1]heptyl-2-endo-amine hydrochloride is a high-purity, chiral bicyclic amine derivative with significant utility in advanced organic synthesis. This compound matters as a sophisticated building block for pharmaceutical research, enabling the construction of complex molecular architectures with precise stereochemical control. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as chiral ligand synthesis and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Chiral Ligand & Catalyst Precursor: Serves as a foundational structure for synthesizing enantioselective catalysts and ligands used in asymmetric synthesis.
• Agrochemical Research: Employed in the design and synthesis of new, stereochemically defined pesticides and herbicides.
• Material Science Monomer: Used in the development of specialized polymers and resins where the rigid bicyclic structure imparts unique thermal and mechanical properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including cycloaddition reactions and stereoselective transformations.

Basic Information

Product Name	3-Endo-Hydroxymethylbicyclo[2.2.1]heptyl-2-endo-amine hydrochloride
CAS No.	205639-89-0
Molecular Formula	C9H16ClNO
Molecular Weight	189.68 g/mol
Synonyms	2-Amino-3-(hydroxymethyl)bicyclo[2.2.1]heptane hydrochloride (endo,endo isomer); (1R,2R,3S,4S)-3-(Aminomethyl)bicyclo[2.2.1]heptane-2-methanol hydrochloride; endo-2-Amino-endo-3-(hydroxymethyl)norbornane hydrochloride; Bicyclo[2.2.1]heptane-2-methanol, 3-(aminomethyl)-, hydrochloride, (1R,2R,3S,4S)-; 2-endo-Amino-3-endo-hydroxymethylnorbornane HCl
EINECS	Contact for details

Quality Control

Our 3-Endo-Hydroxymethylbicyclo[2.2.1]heptyl-2-endo-amine hydrochloride is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC and NMR, to confirm identity, purity (>99%), and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 99.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.