Description

tert-Butyl4-(Isoquinolin-1-Yl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperazine core linked to an isoquinoline moiety. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for synthesizing novel drug candidates. It is primarily needed by R&D laboratories and pharmaceutical manufacturers focused on developing new therapeutics, particularly in areas such as oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Drug Discovery: Employed in the synthesis of potential drug candidates targeting various receptors and enzymes.
• Chemical Synthesis: Serves as a protected piperazine derivative for further functionalization in complex organic syntheses.
• Academic & Industrial R&D: Utilized in research institutions and CROs (Contract Research Organizations) for exploratory chemistry projects.

Basic Information

Product Name	tert-Butyl4-(Isoquinolin-1-Yl)Piperazine-1-Carboxylate
CAS No.	205264-33-1
Molecular Formula	C18H23N3O2
Molecular Weight	313.40 g/mol
Synonyms	1-Boc-4-(isoquinolin-1-yl)piperazine; tert-Butyl 4-(1-isoquinolinyl)-1-piperazinecarboxylate; 1-Piperazinecarboxylic acid, 4-(1-isoquinolinyl)-, 1,1-dimethylethyl ester; 4-(Isoquinolin-1-yl)piperazine-1-carboxylic acid tert-butyl ester; Boc-4-(1-isoquinolinyl)piperazine; 205264-33-1; 1,1-Dimethylethyl 4-(1-isoquinolinyl)-1-piperazinecarboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl4-(Isoquinolin-1-Yl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.