Description

(2R)-2-Amino-2-(2-Naphthyl)Ethan-1-Ol CAS NO 204851-80-9 is a chiral amino alcohol building block characterized by its naphthyl substituent, offering a rigid aromatic scaffold for advanced synthesis. This compound is a critical intermediate for the development of pharmaceuticals, agrochemicals, and chiral catalysts, where its defined stereochemistry is essential for biological activity and material performance. It is primarily sought by research institutions and industrial manufacturers in the fine chemical, pharmaceutical, and material science sectors for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-cancer drug discovery.
• Asymmetric Catalyst Ligand: Used to prepare chiral ligands for transition metal catalysts in enantioselective synthesis, enhancing reaction selectivity and yield.
• Agrochemical Research: Serves as a building block for novel chiral pesticides and herbicides, where specific stereochemistry can influence efficacy and environmental profile.
• Material Science: Employed in the development of chiral polymers, liquid crystals, and advanced organic materials with specific optical properties.
• Academic & Process Chemistry: A valuable reagent for methodological development in organic synthesis and scale-up process optimization.

Basic Information

Product Name	(2R)-2-Amino-2-(2-Naphthyl)Ethan-1-Ol
CAS No.	204851-80-9
Molecular Formula	C₁₂H₁₃NO
Molecular Weight	187.24 g/mol
Synonyms	(R)-2-Amino-2-(naphthalen-2-yl)ethanol; (R)-2-(2-Naphthyl)glycinol; (2R)-2-Amino-2-(naphthalen-2-yl)ethan-1-ol; (R)-2-Naphthylglycinol; (R)-2-(2-Naphthyl)-2-aminoethanol; 2-Naphthaleneethanol, β-amino-, (βR)-; (R)-1-(2-Naphthyl)-2-aminoethanol; (R)-2-Amino-1-(2-naphthyl)ethanol
EINECS	Contact for details

Quality Control

Our (2R)-2-Amino-2-(2-Naphthyl)Ethan-1-Ol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for research and industrial applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.