Description

2-Propenoic-2,3,3-D3Acid(9Ci) is a deuterium-labeled analog of acrylic acid, a fundamental building block in polymer chemistry. This isotopically labeled compound is essential for advanced research and development, enabling precise mechanistic studies and analytical method development. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require deuterated standards for mass spectrometry, NMR spectroscopy, and kinetic isotope effect studies.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative internal standard in LC-MS and GC-MS analysis for the accurate measurement of acrylic acid and its derivatives in complex matrices.
• NMR Spectroscopy Studies: Serves as a crucial probe in nuclear magnetic resonance (NMR) for investigating reaction mechanisms, metabolic pathways, and polymer microstructure without signal interference from protons.
• Kinetic Isotope Effect (KIE) Research: Enables the study of reaction rates and mechanisms in organic synthesis and polymerization processes by tracing the fate of deuterium atoms.
• Pharmaceutical Development: Employed in the synthesis and analysis of deuterated drug candidates (deuterated pharmaceuticals) to potentially improve metabolic stability and pharmacokinetic profiles.
• Polymer Science Research: Used to synthesize labeled polymers for studying polymerization kinetics, degradation mechanisms, and material properties through advanced analytical techniques.
• Environmental and Biochemical Tracing: Applied as a tracer in studies of acrylic acid metabolism in biological systems and its environmental fate.

Basic Information

Item	Detail
Product Name	2-Propenoic-2,3,3-D3Acid(9Ci)
CAS No.	204259-63-2
Molecular Formula	C3D3HO2 or C3H2D3O2
Molecular Weight	~75.08 g/mol
Synonyms	Acrylic-2,3,3-d3 Acid; [2,3,3-2H3]Acrylic Acid; Deuterated Acrylic Acid (d3); 2-Propenoic-2,3,3-d3 Acid; 2,3,3-Trideuteroacrylic Acid; Prop-2-enoic-2,3,3-d3 Acid; (2,3,3-2H3)Prop-2-enoic Acid
EINECS	Contact for details

Quality Control

Every batch of 2-Propenoic-2,3,3-D3Acid(9Ci) undergoes rigorous analytical testing to ensure high chemical purity and isotopic enrichment. Our quality assurance protocol includes verification by NMR, MS, and HPLC to confirm identity, assay, and deuterium incorporation. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment, ensuring traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its nature as a strong acid/organic solvent, keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 98 atom % D
Chemical Purity (NMR)	≥ 97%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.