Description

2-Nitroaniline-3,4,5,6-D4 is a deuterium-labeled isotopologue of 2-nitroaniline, where four hydrogen atoms are replaced with deuterium atoms. This compound is a critical analytical standard and stable isotope-labeled intermediate for advanced research and development. It is primarily utilized by scientists and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors who require high-purity, isotopically labeled materials for mass spectrometry, metabolic studies, and the synthesis of labeled target molecules.

Application

• Internal Standard for Quantitative Analysis: Used as a deuterated internal standard in LC-MS and GC-MS for the accurate quantification of 2-nitroaniline and related compounds in complex matrices.
• Metabolic Pathway Tracing: Serves as a tracer in pharmaceutical and environmental studies to investigate the metabolic fate and degradation pathways of nitroaromatic compounds.
• Synthesis of Labeled Compounds: Acts as a key building block for the synthesis of more complex deuterium-labeled fine chemicals, active pharmaceutical ingredients (APIs), and agrochemicals.
• NMR Spectroscopy: Employed as a probe in nuclear magnetic resonance (NMR) spectroscopy to study molecular structure and dynamics without signal interference from protons.
• Environmental Analysis: Applied in the development and validation of analytical methods for detecting nitroaromatic pollutants in environmental samples.

Basic Information

Product Name	2-Nitroaniline-3,4,5,6-D4
CAS No.	204244-80-4
Molecular Formula	C6H2D4N2O2
Molecular Weight	141.15 g/mol
Synonyms	2-Nitroaniline-d4; Deuterated 2-Nitroaniline; 2-Nitrobenzenamine-3,4,5,6-d4; o-Nitroaniline-d4; 1-Amino-2-nitrobenzene-3,4,5,6-d4; 2-Nitro-1-aminobenzene-d4; [2H4]-2-Nitroaniline; o-Nitro[2H4]aniline
EINECS	Contact for details

Quality Control

Every batch of 2-Nitroaniline-3,4,5,6-D4 is produced and analyzed under strict quality management protocols to ensure exceptional isotopic and chemical purity. Our products undergo rigorous quality testing, including NMR and mass spectrometry, to confirm deuterium incorporation and chemical identity, ensuring compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing isotopic purity, chemical purity, and analytical methods is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Isotopic Purity (D-content)	≥ 98 atom % D
Chemical Purity (HPLC)	≥ 98.0%
Melting Point	71 - 74 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.