Description

5-Aminomethyl-Thiophene-3-Carbonitrile is a versatile heterocyclic building block featuring both amino and nitrile functional groups on a thiophene core. This compound matters as a critical intermediate in modern organic synthesis, enabling the construction of complex molecules for advanced material and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Material Science Precursor: Serves as a monomer or building block for conductive polymers, organic semiconductors, and advanced organic frameworks (MOFs/COFs).
• Ligand and Catalyst Development: The aminomethyl group acts as an anchor for creating novel chelating ligands used in homogeneous catalysis.
• Chemical Biology Probe: Utilized in the synthesis of molecular probes and tags for studying biological systems and enzyme activity.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized thiophene-based dyes and colorants for high-tech applications.

Basic Information

Item	Details
Product Name	5-Aminomethyl-Thiophene-3-Carbonitrile
CAS No.	203792-27-2
Molecular Formula	C6H6N2S
Molecular Weight	138.19 g/mol
Synonyms	3-Cyano-5-thiophenemethylamine; (3-Cyano-5-thienyl)methanamine; 5-(Aminomethyl)thiophene-3-carbonitrile; 3-Thiophenecarbonitrile, 5-(aminomethyl)-; 5-Aminomethyl-3-cyanothiophene; 3-Cyano-5-aminomethylthiophene; 5-Thiophenemethylamine, 3-cyano-
EINECS	Contact for details

Quality Control

Our 5-Aminomethyl-Thiophene-3-Carbonitrile is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure high consistency and reliability for your synthetic workflows. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.