Description

2-Aminopyridine-D6 is a deuterium-labeled isotopologue of 2-aminopyridine, a key building block in organic synthesis and analytical chemistry. This high-purity labeled compound is essential for creating internal standards in mass spectrometry, enabling precise quantification and reducing matrix effects in complex analyses. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical contract research (CRO) industries for drug metabolism and pharmacokinetics (DMPK) studies, environmental analysis, and advanced material science.

Application

• Internal Standard for LC-MS/MS: Serves as a critical, non-interfering reference standard in quantitative bioanalysis for drug discovery and development.
• Metabolite Tracing & Pharmacokinetics: Used in DMPK studies to track the distribution and fate of active pharmaceutical ingredients (APIs) and their metabolites.
• Deuterated Intermediate Synthesis: Acts as a versatile precursor for synthesizing more complex deuterium-labeled compounds for research and diagnostic applications.
• Environmental & Forensic Analysis: Enables accurate detection and measurement of pyridine-based compounds or pollutants in environmental and forensic samples.
• NMR Spectroscopy Solvent & Reagent: Useful as a deuterated reagent or in deuterated solvents for nuclear magnetic resonance (NMR) spectroscopy.
• Mechanistic Reaction Studies: Employed in chemical research to investigate reaction mechanisms and pathways using isotopic labeling techniques.

Basic Information

Product Name	2-Aminopyridine-D6
CAS No.	203784-57-0
Molecular Formula	C5D6N2
Molecular Weight	96.13 g/mol
Synonyms	2-Pyridinamine-D6; 2-Pyridylamine-D6; Pyridin-2-amine-D6; Deuterated 2-Aminopyridine; 2-AP-D6; 2-Amino-D6-pyridine; (2H6)-2-Aminopyridine; 2-Aminopyridine (amino-D6)
EINECS	Contact for details

Quality Control

Our 2-Aminopyridine-D6 is manufactured under strict quality control protocols to ensure high isotopic purity and chemical integrity, suitable for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (atom % D), chemical purity, and identity confirmation. We adhere to cGMP principles where applicable to support regulatory filings in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed in a well-ventilated area and away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Atom % D)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.