Description

Choline Bromide (D13) is a stable isotope-labeled analog of choline bromide, specifically deuterated at 13 positions. This high-purity compound is essential for advanced analytical research, providing a critical internal standard for precise quantification and metabolic pathway tracing. It is primarily utilized by research scientists and quality control laboratories in the pharmaceutical, biotechnology, and academic sectors for applications in mass spectrometry and NMR studies.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference standard in LC-MS and GC-MS analysis of choline and related metabolites in biological samples.
• Metabolic Pathway Tracing: Enables the study of choline metabolism, absorption, and utilization in pharmacokinetic and pharmacodynamic research.
• NMR Spectroscopy: Serves as a deuterated solvent or a probe for structural analysis and dynamic studies in nuclear magnetic resonance.
• Pharmaceutical R&D: Critical for the development and validation of analytical methods for drug substances and products containing choline.
• Biomarker Research: Facilitates the accurate measurement of choline as a potential biomarker in clinical and diagnostic studies.
• Nutraceutical Analysis: Employed in the quality control and assurance of dietary supplements and fortified foods.

Basic Information

Product Name	Choline Bromide (D13)
CAS No.	203645-64-1
Molecular Formula	C5D13BrNO
Molecular Weight	187.12 g/mol (for C5D13BrNO)
Synonyms	(2-Hydroxyethyl)trimethylammonium Bromide-d13; Deuterated Choline Bromide; Choline-d13 Bromide; (2-Hydroxyethyl-d4)trimethyl-d9-ammonium Bromide; Choline Bromide-d13; N,N,N-Trimethyl-d9-2-hydroxyethyl-d4-ammonium Bromide; 2-Hydroxy-N,N,N-trimethyl-d9-ethanaminium-d4 Bromide
EINECS	Contact for details

Quality Control

Every batch of Choline Bromide (D13) is manufactured and tested under strict quality management systems. We guarantee high chemical purity and isotopic enrichment, supported by comprehensive analytical documentation. A Certificate of Analysis (COA) is provided with each shipment, detailing results for assay, isotopic purity, and specific impurities. Our quality commitment ensures reliability for your most sensitive research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 99 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.