Description

n-Methyl-D3-Caprolactam is a deuterated derivative of N-methylcaprolactam, where three hydrogen atoms are replaced by deuterium. This isotopic labeling makes it an invaluable internal standard and tracer in quantitative mass spectrometry and NMR spectroscopy, ensuring precise analytical measurements. It is primarily required by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for drug metabolism studies, pharmacokinetic research, and the development of deuterated active pharmaceutical ingredients (APIs).

Application

• Internal Standard for LC-MS/MS and GC-MS analysis in bioanalytical studies.
• Deuterated tracer in metabolic pathway and pharmacokinetic research.
• Precursor in the synthesis of deuterium-labeled pharmaceutical compounds.
• NMR spectroscopy standard for structural elucidation and quantification.
• Research chemical for studying reaction mechanisms and isotope effects.
• Component in the development of specialty polymers and advanced materials requiring isotopic labeling.

Basic Information

Product Name	n-Methyl-D3-Caprolactam
CAS No.	203645-60-7
Molecular Formula	C7H10D3NO
Molecular Weight	129.20 g/mol
Synonyms	N-Methylcaprolactam-d3; 1-Methylazepan-2-one-d3; Hexahydro-1-methyl-2H-azepin-2-one-d3; Deuterated N-Methylcaprolactam; N-Methyl-ε-caprolactam-d3; Caprolactam, N-methyl-, d3-; 2H-Azepin-2-one, hexahydro-1-methyl-, d3-
EINECS	Contact for details

Quality Control

Our n-Methyl-D3-Caprolactam is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR and mass spectrometry, to confirm isotopic purity (D-enrichment) and chemical purity. A comprehensive Certificate of Analysis (COA) detailing assay, isotopic enrichment level, and impurity profile is provided with every shipment to ensure it meets the exacting standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.