Description

2-Mercaptoethanol-D6 is a deuterium-labeled isotopologue of 2-mercaptoethanol, a critical reagent in analytical chemistry and life sciences research. This high-purity, isotopically enriched compound is essential for creating internal standards in mass spectrometry, enabling precise quantification and reducing matrix effects. It is primarily utilized by analytical chemists, pharmaceutical researchers, and metabolomics specialists working in drug development, environmental analysis, and biochemical pathway studies.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference standard in LC-MS and GC-MS analyses for accurate measurement of 2-mercaptoethanol and related thiols.
• Metabolomics and Proteomics Research: Facilitates the study of metabolic pathways and protein structures through stable isotope labeling techniques.
• Pharmaceutical Development: Employed in pharmacokinetic (PK) and bioanalytical studies to track drug metabolites and ensure regulatory compliance in assays.
• Environmental Analysis: Aids in the detection and quantification of thiol-based compounds in complex environmental samples.
• NMR Spectroscopy: Serves as a deuterated solvent or shift reagent in nuclear magnetic resonance studies.
• Chemical Synthesis: Acts as a deuterium-labeled building block or reducing agent in the synthesis of specialized organic compounds and pharmaceuticals.

Basic Information

Product Name	2-Mercaptoethanol-D6
CAS No.	203645-37-8
Molecular Formula	C2D6OS
Molecular Weight	84.18 g/mol
Synonyms	2-Hydroxyethyl-1,1,2,2-d4-d2 Mercaptan; 2-Mercaptoethanol-d6; β-Mercaptoethanol-d6; Ethylene-d4 glycol-d2 monothiol; 1,1,2,2-Tetradeutero-2-(dideuteriothio)ethanol; Deuterated 2-Mercaptoethanol; HSCH2CH2OD-d5; Thioethylene-d4 glycol-d2
EINECS	Contact for details

Quality Control

Every batch of 2-Mercaptoethanol-D6 is produced and analyzed under strict quality management protocols to ensure the highest isotopic and chemical purity. Our products undergo rigorous quality testing, including NMR and mass spectrometry, to confirm deuterium enrichment and chemical identity. Certificates of Analysis (COA) detailing batch-specific results for purity, isotopic enrichment, and other critical parameters are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C. Due to its highly volatile and easily oxidized nature, prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.