Description

Tetrahydro-Pyran-4-Thiol CAS NO 203246-71-3 is a versatile sulfur-containing heterocyclic building block, characterized by its reactive thiol functional group. This compound is crucial for the synthesis of complex molecules, offering chemists a valuable handle for constructing pharmacophores and advanced materials. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and ligand synthesis.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral targets.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the thiol group acts as a critical linker or functional moiety.
• Ligand and Catalyst Preparation: Serves as a precursor for chelating ligands in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of functional polymers and advanced organic materials requiring specific sulfur-based properties.
• Chemical Biology Probes: Utilized in the design of probes and inhibitors for studying enzyme activity and biological pathways.
• Flavor & Fragrance Industry: Acts as a potential intermediate for creating sulfur-containing aroma compounds.

Basic Information

Product Name	Tetrahydro-Pyran-4-Thiol
CAS No.	203246-71-3
Molecular Formula	C5H10OS
Molecular Weight	118.20 g/mol
Synonyms	4-Mercaptotetrahydropyran; Tetrahydro-4H-pyran-4-thiol; 4-Thiotetrahydropyran; 4-Pyranthiol, tetrahydro-; THP-4-thiol; 4-Mercaptotetrahydro-2H-pyran; 4-Sulfanyloxane
EINECS	Contact for details

Quality Control

Our Tetrahydro-Pyran-4-Thiol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed chromatographic data (GC/HPLC) are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its easily oxidized nature, minimize exposure to air during handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.