Description

1,2-Epoxypropane-D6 is a deuterated analog of propylene oxide, where six hydrogen atoms are replaced by deuterium, a stable isotope of hydrogen. This isotopic labeling makes it an essential tool in advanced research, particularly in mechanistic studies and analytical chemistry, where it serves as an internal standard for mass spectrometry. It is primarily required by pharmaceutical R&D laboratories, academic research institutions, and specialty chemical manufacturers engaged in metabolic pathway tracing, pharmacokinetic studies, and the synthesis of labeled compounds.

Application

• Internal Standard for Mass Spectrometry (MS): Used for the accurate quantification of propylene oxide and related compounds in complex matrices via GC-MS or LC-MS.
• Metabolic and Pharmacokinetic Research: Acts as a tracer in studies to elucidate drug metabolism pathways and absorption, distribution, metabolism, and excretion (ADME) profiles.
• Mechanistic Reaction Studies: Employed in chemical and biochemical research to investigate reaction mechanisms and intermediates using spectroscopic techniques like NMR.
• Synthesis of Deuterated Compounds: Serves as a key building block for the preparation of other deuterium-labeled fine chemicals and active pharmaceutical ingredients (APIs).
• Environmental and Toxicological Analysis: Facilitates precise measurement of propylene oxide exposure levels in environmental and occupational health studies.

Basic Information

Product Name	1,2-Epoxypropane-D6
CAS No.	202468-69-7
Molecular Formula	C3D6O
Molecular Weight	64.12 g/mol
Synonyms	Propylene Oxide-d6; Methyloxirane-d6; 1,2-Propylene Oxide-d6; (2H6)Propylene Oxide; Epoxypropane-d6; 2-Methyloxirane-d6; Deuterated Propylene Oxide; Propene Oxide-d6
EINECS	Contact for details

Quality Control

Our 1,2-Epoxypropane-D6 is produced and handled under strict quality management protocols to ensure isotopic purity and chemical integrity, critical for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (D-atom %), chemical purity, and solvent residues. We adhere to relevant industry standards for high-purity labeled compounds, ensuring reliability and consistency for your research needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated place, ideally at 2-8°C. Keep away from heat, sparks, and open flames. Containers should be kept tightly sealed when not in use to prevent evaporation and potential moisture ingress.

Specification

Item	Specification
Appearance	Colorless liquid
Identification (IR)	Conforms to reference spectrum
Isotopic Purity (D-atom %)	≥ 98%
Chemical Purity (GC)	≥ 99.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.