Description

5-Amino-1-(2-Fluorobenzyl)-1H-Indazole is a high-purity, advanced pharmaceutical intermediate characterized by its unique indazole core structure. This compound is critical for the synthesis of novel, targeted therapeutic agents, offering researchers and manufacturers a reliable building block for complex molecular architectures. It is primarily utilized by pharmaceutical R&D teams and fine chemical producers engaged in developing new drug candidates, particularly in oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent kinase inhibitors and other targeted small-molecule drugs.
• Oncology Research: Serves as a core scaffold for developing novel anti-cancer compounds due to its indazole pharmacophore.
• CNS Drug Discovery: Used in research programs targeting neurological disorders, leveraging its ability to cross the blood-brain barrier.
• Chemical Biology: Employed as a probe or labeled compound in biochemical assays to study enzyme mechanisms.
• Process Chemistry: Utilized in scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	5-Amino-1-(2-Fluorobenzyl)-1H-Indazole
CAS No.	202197-30-6
Molecular Formula	C₁₄H₁₂FN₃
Molecular Weight	241.27 g/mol
Synonyms	5-Amino-1-[(2-fluorophenyl)methyl]-1H-indazole; 1-(2-Fluorobenzyl)-1H-indazol-5-amine; 5-Amino-1-(2-fluorobenzyl)indazole; 202197-30-6; 5-Amino-1-(2-fluorobenzyl)-1H-indazole; 1H-Indazole, 5-amino-1-[(2-fluorophenyl)methyl]-
EINECS	Contact for details

Quality Control

Every batch of 5-Amino-1-(2-Fluorobenzyl)-1H-Indazole is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep away from oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.