Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 3-Amino-, (1S,2S,3R,4R)- (9Ci) is a high-purity, stereochemically defined chiral building block essential for advanced organic synthesis. Its rigid norbornene scaffold and strategically positioned amino and carboxylic acid functional groups make it a versatile precursor for constructing complex molecular architectures. This compound is critically needed by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients and chiral catalysts.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Ligand & Catalyst Development: Serves as a precursor for creating sophisticated chiral ligands used in asymmetric catalysis (e.g., hydrogenation, cycloaddition).
• Agrochemical Synthesis: Building block for developing new, stereoselective pesticides and herbicides with enhanced efficacy.
• Material Science Monomer: Used in the synthesis of specialty polymers with unique thermal and mechanical properties derived from the norbornene structure.
• Peptidomimetics & Bio-conjugation: The amino and carboxyl groups facilitate its incorporation into peptide analogs or as a linker for bioconjugation strategies.
• Academic & Process Chemistry Research: A valuable tool for methodological studies in organic synthesis and scale-up process development.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 3-Amino-, (1S,2S,3R,4R)- (9Ci)
CAS No.	202187-27-7
Molecular Formula	C9H11NO2
Molecular Weight	165.19 g/mol
Synonyms	(1S,2S,3R,4R)-3-Aminobicyclo[2.2.1]hept-5-ene-2-carboxylic acid; (1S,2S,3R,4R)-3-Amino-2-norbornene-5-carboxylic acid; endo-3-Aminonorborn-5-ene-2-exo-carboxylic acid; 3-Amino-2-norbornene-5-carboxylic acid (specific isomer); Chiral Norbornene Amino Acid; Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 3-amino-, (1S,2S,3R,4R)-; 202187-27-7
EINECS	Contact for details

Quality Control

Our production of this chiral building block adheres to strict quality protocols to ensure batch-to-batch consistency and high stereochemical purity, critical for sensitive synthetic applications. Quality is verified through advanced analytical techniques including Chiral HPLC and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.