Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 3-Amino-, (1R,2R,3S,4S)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its rigid bicyclic framework and strategically positioned amino and carboxylic acid functional groups make it a versatile precursor for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where its unique structure can contribute to biological activity and selectivity.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis to control stereochemistry.
• Material Science: Potential building block for specialty polymers and advanced materials requiring rigid, functionalized monomers.
• Academic & R&D: Employed in fundamental organic chemistry research to explore new reaction methodologies and construct complex natural product analogs.
• Peptidomimetics: The constrained structure is valuable for designing peptide mimics with enhanced metabolic stability and bioavailability.

Basic Information

Item	Details
Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 3-Amino-, (1R,2R,3S,4S)- (9Ci)
CAS No.	202187-24-4
Molecular Formula	C9H11NO2
Molecular Weight	165.19 g/mol
Synonyms	(1R,2R,3S,4S)-3-Aminobicyclo[2.2.1]hept-5-ene-2-carboxylic acid; endo-3-Aminobicyclo[2.2.1]hept-5-ene-2-carboxylic acid (specific stereoisomer); 3-Amino-2-norbornene-2-carboxylic acid (stereospecific); Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 3-amino-, (1R,2R,3S,4S)-; (1R,2R,3S,4S)-3-Amino-2-norbornene-2-carboxylic acid; endo-3-Amino-5-norbornene-2-carboxylic acid; Chiral NBOC acid derivative
EINECS	Contact for details

Quality Control

Our production of Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 3-Amino-, (1R,2R,3S,4S)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, and chiral analysis to confirm identity, assay purity, and enantiomeric/excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.