Description

Bicyclo[2.2.1]Heptane-2-Carboxylic Acid, 3-Amino-, (1S,2S,3R,4R)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its rigid, polycyclic "norbornane" core and strategically positioned amino and carboxylic acid functional groups make it a versatile precursor for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in asymmetric synthesis, medicinal chemistry, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or requiring specific three-dimensional shape for receptor binding.
• Asymmetric Catalyst Ligand Precursor: Used to synthesize novel chiral ligands for transition metal catalysis, enabling highly enantioselective transformations in fine chemical production.
• Agrochemical Research: Serves as a building block for novel herbicides, fungicides, or insecticides where the rigid norbornane structure can impart favorable biological activity and environmental stability.
• Material Science Monomer: Potential use in the synthesis of specialty polymers with unique thermal and mechanical properties due to its strained bicyclic framework.
• Peptidomimetics & Bioactive Molecule Design: The structure mimics constrained amino acids, making it valuable for creating peptide analogs with enhanced metabolic stability and potency.

Basic Information

Product Name	Bicyclo[2.2.1]Heptane-2-Carboxylic Acid, 3-Amino-, (1S,2S,3R,4R)- (9Ci)
CAS No.	202187-22-2
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	(1S,2S,3R,4R)-3-Aminobicyclo[2.2.1]heptane-2-carboxylic acid; (1S,2S,3R,4R)-3-Amino-2-norbornanecarboxylic acid; endo-3-Amino-2-norbornanecarboxylic acid (specific stereoisomer); 3-Amino-2-norbornanecarboxylic acid; Bicyclo[2.2.1]heptane-2-carboxylic acid, 3-amino-, (1S,2S,3R,4R)-; Chiral Norbornane Amino Acid
EINECS	Contact for details

Quality Control

We supply Bicyclo[2.2.1]Heptane-2-Carboxylic Acid, 3-Amino-, (1S,2S,3R,4R)- (9Ci) under a strict quality management system. Every batch is characterized and tested to ensure identity, purity, and stereochemical integrity, meeting the exacting standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing chiral purity (by chiral HPLC), chemical purity (by HPLC), and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.