Description

(4S)-4-Bromomethyl-2-Phenyl-1,3-Dioxane is a chiral building block of significant interest in advanced organic synthesis. Its value lies in its unique structure, which incorporates both a reactive bromomethyl handle and a protected diol moiety, enabling stereoselective construction of complex molecules. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting specific stereocenters.
• Asymmetric Synthesis: Used as a precursor in the preparation of chiral ligands, catalysts, and other auxiliaries essential for enantioselective reactions.
• Natural Product Synthesis: Serves as a building block for the stereocontrolled synthesis of complex natural products and their analogs.
• Agrochemical Research: Employed in the development of novel, chiral active ingredients for crop protection with potentially improved efficacy and environmental profiles.
• Material Science Precursor: Can be utilized in the synthesis of specialized monomers for advanced polymeric materials.

Basic Information

Product Name	(4S)-4-Bromomethyl-2-Phenyl-1,3-Dioxane
CAS No.	201743-52-4
Molecular Formula	C11H13BrO2
Molecular Weight	257.12 g/mol
Synonyms	(4S)-4-(Bromomethyl)-2-phenyl-1,3-dioxane; (S)-4-(Bromomethyl)-2-phenyl-1,3-dioxane; 2-Phenyl-4-bromomethyl-1,3-dioxane, (4S)-; 1,3-Dioxane, 4-(bromomethyl)-2-phenyl-, (4S)-; (S)-4-Bromomethyl-2-phenyl-1,3-dioxane; 4-Bromomethyl-2-phenyl-1,3-dioxane (S enantiomer)
EINECS	Contact for details

Quality Control

Our (4S)-4-Bromomethyl-2-Phenyl-1,3-Dioxane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.