Description

(5S)-5-Phenyl-3,5-Dimethylimidazolidine-2,4-Dione is a chiral, non-proteinogenic amino acid derivative belonging to the hydantoin class of heterocyclic compounds. This compound serves as a versatile and high-value building block in advanced organic synthesis, particularly for the development of pharmaceuticals and fine chemicals. It is primarily needed by research institutions, pharmaceutical R&D departments, and specialty chemical manufacturers engaged in creating novel active ingredients, chiral catalysts, or complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potential drug candidates, especially those targeting neurological or metabolic disorders.
• Asymmetric Synthesis: Utilized as a building block or auxiliary in the preparation of enantiomerically pure compounds for agrochemicals and advanced materials.
• Peptidomimetics Research: Incorporated into peptide analogs to study structure-activity relationships and improve metabolic stability.
• Ligand and Catalyst Development: Serves as a scaffold for creating novel chiral ligands used in transition metal catalysis.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	(5S)-5-Phenyl-3,5-Dimethylimidazolidine-2,4-Dione
CAS No.	201607-11-6
Molecular Formula	C11H12N2O2
Molecular Weight	204.23 g/mol
Synonyms	(5S)-5-Phenyl-5-methylhydantoin; (S)-5-Phenyl-5-methylhydantoin; (S)-5-Methyl-5-phenylhydantoin; (S)-5-Phenyl-3,5-dimethylimidazolidine-2,4-dione; L-5-Phenyl-5-methylhydantoin; 5-Methyl-5-phenylhydantoin (S-enantiomer); 2,4-Imidazolidinedione, 5-phenyl-3,5-dimethyl-, (5S)-
EINECS	Contact for details

Quality Control

Our (5S)-5-Phenyl-3,5-Dimethylimidazolidine-2,4-Dione is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.