Description

(R)-1-Methylmephenytoin is a chiral intermediate of significant importance in pharmaceutical research and development. This compound is valued for its role in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), where stereochemistry is critical for biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) agents and other specialized therapeutics.

Application

• Key chiral building block for the synthesis of pharmaceutical compounds.
• Intermediate in the research and development of central nervous system (CNS) active drugs.
• Used in stereoselective synthesis to produce enantiomerically pure target molecules.
• Reference standard for analytical method development and validation in pharmaceutical quality control.
• Precursor in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Critical material for process chemistry development and scale-up of chiral APIs.

Basic Information

Product Name	(R)-1-Methylmephenytoin
CAS No.	201606-44-2
Molecular Formula	C12H14N2O2
Molecular Weight	218.25 g/mol
Synonyms	(R)-Methylphenytoin; (R)-1-Methyl-5,5-diphenylimidazolidine-2,4-dione; (R)-1-Methyl-5,5-diphenylhydantoin; (R)-Nirvanol; (R)-Enantiomer of Mephenytoin; (R)-Methoin; (R)-1-Methylphenytoin; (5R)-1-Methyl-5,5-diphenylimidazolidine-2,4-dione
EINECS	Contact for details

Quality Control

Our (R)-1-Methylmephenytoin is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.