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B-Amino-4-Bromobenzeneethanol CAS NO 201403-02-3


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CAS No.:201403-02-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

B-Amino-4-Bromobenzeneethanol is a versatile brominated aniline derivative with a pendant ethanol group, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its unique structure, combining an aromatic amine with a bromine substituent and a hydroxymethyl chain, makes it invaluable for constructing complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and functional materials.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and as a building block for kinase inhibitors.
  • Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators, leveraging the reactivity of the bromine and amino groups.
  • Ligand and Catalyst Preparation: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
  • Dye and Pigment Manufacturing: Intermediate for producing high-performance, bromine-containing dyes and organic pigments with enhanced lightfastness.
  • Polymer Science: Monomer or cross-linking agent for creating specialty polymers, such as epoxy resins and polyurethanes, with specific functional properties.
  • Chemical Research & Development: A valuable reagent for academic and industrial R&D in medicinal chemistry and material science for structure-activity relationship (SAR) studies.

Basic Information

Product Name B-Amino-4-Bromobenzeneethanol
CAS No. 201403-02-3
Molecular Formula C8H10BrNO
Molecular Weight 216.08 g/mol
Synonyms 2-(4-Bromo-2-aminophenyl)ethanol; 4-Bromo-2-aminophenethyl alcohol; 2-Amino-5-bromophenethyl alcohol; (4-Bromo-2-aminophenyl)ethanol; 2-(2-Amino-5-bromophenyl)ethan-1-ol; 5-Bromo-2-aminophenylethanol; β-Amino-4-bromophenylethanol; 201403-02-3
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Quality Control

Our B-Amino-4-Bromobenzeneethanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity, potency, and impurity profiles. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production facilities adhere to cGMP guidelines where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference standard
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm
Related Substances (HPLC) Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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