Description

1-o-Hexadecyl-(7,7,8,8-D4)-Sn-Glyceryl-3-Phosphorylcholine is a deuterated analog of a key phospholipid, specifically designed for advanced research and analytical applications. This compound is crucial for metabolic and pharmacokinetic studies, where its stable isotope labeling allows for precise tracking and quantification without interfering with biological pathways. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life sciences sectors for lipidomics, tracer studies, and as an internal standard in mass spectrometry.

Application

• Internal Standard for Mass Spectrometry: Used for the accurate quantification of natural phospholipids in complex biological matrices via LC-MS/MS.
• Metabolic Tracer Studies: Enables detailed investigation of phospholipid metabolism, biosynthesis, and turnover in cell culture and animal models.
• Lipidomics Research: A critical tool in profiling and understanding lipid composition and dynamics in disease states like cancer, metabolic disorders, and neurodegeneration.
• Drug Delivery Research: Serves as a deuterated component in the study of liposomal formulations and nanoparticle drug carriers.
• Biomarker Discovery: Facilitates the identification and validation of lipid-based biomarkers by providing a stable isotopic reference.
• Pharmaceutical R&D: Supports ADME (Absorption, Distribution, Metabolism, Excretion) studies for novel therapeutics targeting lipid pathways.

Basic Information

Product Name	1-o-Hexadecyl-(7,7,8,8-D4)-Sn-Glyceryl-3-Phosphorylcholine
CAS No.	201216-37-7
Molecular Formula	C₂₇H₅₄D₄NO₇P
Molecular Weight	~ 547.7 g/mol (Contact for exact weight)
Synonyms	Deuterated Lyso-PAF C-16 (d4); 1-O-Hexadecyl-2-lyso-sn-glycero-3-phosphocholine (7,7,8,8-d4); 1-O-Hexadecyl-2-hydroxy-sn-glycero-3-phosphocholine-d4; Lyso-Platelet-Activating Factor C-16-d4; 1-Hexadecyl-2-lyso-sn-glycero-3-phosphocholine-d4; Deuterated Lyso-GPC(16:0/0:0); PAF Lyso-derivative-d4; sn-Glycero-3-phosphocholine, 1-O-hexadecyl-2-hydroxy-, (7,7,8,8-d4)
EINECS	Contact for details

Quality Control

Our deuterated phospholipids are produced under strict quality control protocols to ensure high isotopic purity and chemical integrity, essential for sensitive analytical applications. Each batch is characterized by advanced techniques including NMR and mass spectrometry to confirm deuteration level and structural identity. Certificates of Analysis (COA) detailing purity, isotopic enrichment, and analytical data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity (TLC)	Single spot
Solubility	Soluble in chloroform, methanol, ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.