Description

1H-Indole-1-Carboxamide, 2,3-Dihydro-5-Methyl-n-[6-[(2-Methyl-3-Pyridinyl)Oxy]-3-Pyridinyl]-6-(Trifluoromethyl)- is a high-purity, complex heterocyclic compound of significant interest in advanced chemical synthesis. This specialized intermediate is valued for its unique molecular scaffold, which incorporates indole, pyridine, and trifluoromethyl functionalities. It is primarily sought after by research institutions and pharmaceutical development teams engaged in the discovery and optimization of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the research and development of new active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a key scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biochemical Tool Compound: Employed in biological assays to investigate specific enzyme inhibition or receptor modulation pathways.
• Advanced Organic Synthesis: Acts as a versatile precursor for synthesizing more complex, functionalized heterocyclic compounds in academic and industrial R&D settings.
• Contract Research & Manufacturing (CRMO): Supplied to organizations providing custom synthesis and process development services for the life sciences industry.

Basic Information

Product Name	1H-Indole-1-Carboxamide, 2,3-Dihydro-5-Methyl-n-[6-[(2-Methyl-3-Pyridinyl)Oxy]-3-Pyridinyl]-6-(Trifluoromethyl)-
CAS No.	200940-22-3
Molecular Formula	C25H21F3N4O2
Molecular Weight	466.46 g/mol
Synonyms	2,3-Dihydro-5-methyl-N-[6-[(2-methyl-3-pyridinyl)oxy]-3-pyridinyl]-6-(trifluoromethyl)-1H-indole-1-carboxamide; 6-(Trifluoromethyl)-2,3-dihydro-5-methyl-N-[6-[(2-methyl-3-pyridinyl)oxy]-3-pyridinyl]-1H-indole-1-carboxamide; UNII-3J3U4WY9QN; 3J3U4WY9QN; BMS-599626; BMS599626; BMS 599626; AC1L1BWB
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure structural identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and analytical data is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.