Description

6-Difluoromethoxyindole is a high-purity fluorinated indole derivative, a critical building block in advanced organic synthesis. Its value lies in the unique reactivity and electronic properties imparted by the difluoromethoxy group, enabling the development of novel compounds with enhanced biological activity and metabolic stability. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atoms can improve lipophilicity and environmental stability.
• Material Science Research: Serves as a precursor for functionalized organic materials and specialty polymers.
• Fluorine Chemistry Studies: An important compound for investigating the effects of fluorinated alkoxy substituents on indole ring systems.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	6-Difluoromethoxyindole
CAS No.	200207-21-2
Molecular Formula	C9H7F2NO
Molecular Weight	183.16 g/mol
Synonyms	1H-Indole, 6-(difluoromethoxy)-; 6-(Difluoromethoxy)-1H-indole; Indole, 6-difluoromethoxy-; 6-Difluoromethoxy-1H-indole; 200207-21-2; 6-(Difluoromethoxy)indole
EINECS	Contact for details

Quality Control

Our 6-Difluoromethoxyindole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.