Description

1,2,3,4-Tetrahydroisoquinoline-7-Carbonitrile Hydrochloride CAS NO 200137-81-1 is a high-purity, pharmaceutically relevant organic salt belonging to the tetrahydroisoquinoline class of compounds. This chemical serves as a critical advanced intermediate in the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by pharmaceutical R&D laboratories and contract manufacturing organizations (CMOs) for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of drug candidates targeting neurological and cardiovascular disorders.
• Organic Synthesis Reagent: Used in research-scale and pilot-scale organic reactions, including cyclizations and functional group transformations.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and validation in quality control laboratories.
• Agrochemical Research: Potential intermediate in the development of novel crop protection agents and pesticides.
• Academic & Institutional Research: Used in universities and research institutes for studying heterocyclic chemistry and medicinal chemistry pathways.

Basic Information

Product Name	1,2,3,4-Tetrahydroisoquinoline-7-Carbonitrile Hydrochloride
CAS No.	200137-81-1
Molecular Formula	C10H10N2·HCl
Molecular Weight	194.66 g/mol
Synonyms	7-Cyano-1,2,3,4-tetrahydroisoquinoline hydrochloride; 1,2,3,4-Tetrahydro-7-isoquinolinecarbonitrile hydrochloride; THIQ-7-CN HCl; 7-CN-THIQ HCl; 1,2,3,4-Tetrahydroisoquinoline-7-carbonitrile HCl; 7-Cyano-1,2,3,4-tetrahydroisoquinoline HCl; 200137-81-1
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydroisoquinoline-7-Carbonitrile Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.