Description

2-Azabicyclo[2.2.1]Hept-5-En-3-One, 2-Acetyl-, (1S,4R)- (9Ci) is a high-value, stereochemically defined bicyclic lactam derivative, serving as a critical chiral building block in advanced organic synthesis. Its rigid, functionalized structure makes it an indispensable precursor for constructing complex molecular architectures with precise stereochemical control. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in neurological and antiviral therapeutic areas.
• Asymmetric Catalysis Ligand Precursor: Used to develop novel chiral ligands and organocatalysts for enantioselective transformations.
• Agrochemical Research: Serves as a building block for creating novel, stereospecific pesticides and herbicides.
• Academic & R&D: Employed in methodological studies and the total synthesis of natural products.
• Fine Chemical Synthesis: Utilized in the production of specialty chemicals requiring the 7-oxabicyclo[2.2.1]heptane skeleton.

Basic Information

Product Name	2-Azabicyclo[2.2.1]Hept-5-En-3-One, 2-Acetyl-, (1S,4R)- (9Ci)
CAS No.	200002-40-0
Molecular Formula	C8H9NO2
Molecular Weight	151.16 g/mol
Synonyms	(1S,4R)-2-Acetyl-2-azabicyclo[2.2.1]hept-5-en-3-one; 2-Acetyl-2-azabicyclo[2.2.1]hept-5-en-3-one, (1S,4R)-; (1S,4R)-2-Acetyl-3-oxo-2-azabicyclo[2.2.1]hept-5-ene; 2-Acetyl-3-oxo-2-azabicyclo[2.2.1]hept-5-ene, (1S,4R)-; (1S,4R)-2-Acetyl-2-azabicyclo[2.2.1]hept-5-en-3-one (9CI); 2-Azabicyclo[2.2.1]hept-5-en-3-one, 2-acetyl-, (1S,4R)-; (1S,4R)-rel-2-Acetyl-2-azabicyclo[2.2.1]hept-5-en-3-one
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be sensitive to moisture and prolonged exposure to air; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.