Description

2-tert-Butyl-1H-Indole-3-Carbaldehyde is a versatile indole derivative, a key synthetic intermediate prized for its unique sterically hindered structure. This compound matters for its role in constructing complex molecules, particularly in the development of advanced pharmaceuticals and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the tert-butyl group can influence biological activity and stability.
• Material Science Research: Serves as a precursor for organic semiconductors, dyes, and photochromic materials due to its electron-rich indole core and formyl functionality.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Academic & Industrial R&D: A valuable reagent for methodological chemistry research, including studies on heterocyclic chemistry and new catalytic transformations.

Basic Information

Product Name	2-tert-Butyl-1H-Indole-3-Carbaldehyde
CAS No.	29957-81-1
Molecular Formula	C₁₃H₁₅NO
Molecular Weight	201.27 g/mol
Synonyms	2-tert-Butylindole-3-carboxaldehyde; 2-(tert-Butyl)-1H-indole-3-carbaldehyde; 3-Formyl-2-tert-butylindole; 2-tert-Butyl-1H-indole-3-carboxaldehyde; 2-tert-Butylindole-3-carbaldehyde; 1H-Indole-3-carboxaldehyde, 2-(1,1-dimethylethyl)-; 2-(tert-Butyl)-1H-indole-3-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-tert-Butyl-1H-Indole-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.