Description

Dimethyl N,n-Diisopropylphosphoramidite is a highly reactive organophosphorus compound widely used as a key building block in organic synthesis. Its primary value lies in its role as a versatile phosphitylating agent, crucial for the formation of phosphite and phosphoramidite intermediates. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly in nucleotide synthesis and catalyst development.

Application

• Phosphoramidite Intermediate in Oligonucleotide Synthesis: A critical reagent for the automated solid-phase synthesis of DNA and RNA sequences.
• Ligand Precursor for Catalysis: Used in the preparation of chiral phosphite and phosphoramidite ligands for asymmetric hydrogenation and other metal-catalyzed reactions.
• Agrochemical Synthesis: Serves as a building block for creating novel phosphorus-containing active ingredients.
• Pharmaceutical Intermediate: Employed in the synthesis of nucleotide analogs and other bioactive molecules.
• Material Science: Used in the development of flame retardants and specialty polymers.
• Chemical Research & Development: A valuable tool for exploring new phosphorus chemistry and creating custom molecular architectures.

Basic Information

Product Name	Dimethyl N,n-Diisopropylphosphoramidite
CAS No.	29952-64-5
Molecular Formula	C8H20NO2P
Molecular Weight	193.22 g/mol
Synonyms	Diisopropylaminodimethoxyphosphine; N,N-Diisopropylphosphoramidic Acid Dimethyl Ester; Dimethoxy-N,N-diisopropylaminophosphine; Phosphoramidic Acid, N,N-Diisopropyl-, Dimethyl Ester; P,P-Dimethyl N,N-Diisopropylphosphoramidite; (Dimethoxyphosphanyl)-N,N-diisopropylamine
EINECS	Contact for details

Quality Control

Our Dimethyl N,n-Diisopropylphosphoramidite is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR and GC analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Due to its moisture-sensitive and easily oxidized nature, containers should be purged with inert gas after each opening.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (Karl Fischer)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.