Description

(5S,7R)-5-Ethyl-1,4,5,6,7,8,9,10-Octahydro-2H-3,7-Methanoazacycloundecino[5,4-B]Indol-5-Ol is a complex, stereochemically defined heterocyclic compound that serves as a critical advanced intermediate in pharmaceutical synthesis. Its value lies in its unique fused ring structure, which makes it a versatile building block for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and neurological research. This high-purity compound is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in process development and the synthesis of complex therapeutic molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block in the multi-step synthesis of complex drug candidates, especially those targeting neurological pathways.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new pharmacophores.
• Process Chemistry: Serves as a critical intermediate in scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in API manufacturing.
• Asymmetric Synthesis: Utilized in chiral synthesis due to its defined (5S,7R) stereochemistry, enabling the production of enantiomerically pure final compounds.

Basic Information

Product Name	(5S,7R)-5-Ethyl-1,4,5,6,7,8,9,10-Octahydro-2H-3,7-Methanoazacycloundecino[5,4-B]Indol-5-Ol
CAS No.	29951-44-8
Molecular Formula	C19H25NO2
Molecular Weight	299.41 g/mol
Synonyms	5-Ethyl-1,4,5,6,7,8,9,10-octahydro-2H-3,7-methanoazacycloundecino[5,4-b]indol-5-ol, (5S,7R)-; (5S,7R)-5-Ethyl-5-hydroxy-1,4,5,6,7,8,9,10-octahydro-2H-3,7-methanoazacycloundecino[5,4-b]indole; 3,7-Methanoazacycloundecino[5,4-b]indol-5-ol, 5-ethyl-1,4,5,6,7,8,9,10-octahydro-2H-, (5S,7R)-; Yohimbane derivative
EINECS	Contact for details

Quality Control

Our (5S,7R)-5-Ethyl-1,4,5,6,7,8,9,10-Octahydro-2H-3,7-Methanoazacycloundecino[5,4-B]Indol-5-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support custom synthesis and purification to meet specific project requirements, including chiral purity and stringent impurity limits.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere to prevent degradation. For long-term storage, consider storing under an inert gas such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (5S,7R)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.