Description

tert-Butylchloroisopropylphosphine is a highly reactive organophosphorus compound, specifically a chlorophosphine, that serves as a critical building block in advanced chemical synthesis. Its value lies in its role as a versatile ligand precursor and a key reagent for introducing the sterically demanding tert-butylphosphino group into complex molecular architectures. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors, particularly for developing catalysts and fine chemicals where precise steric and electronic control is required.

Application

• Pharmaceutical Intermediate Synthesis: A key precursor for creating novel phosphine ligands used in asymmetric catalysis and cross-coupling reactions (e.g., Suzuki, Heck).
• Agrochemical Active Ingredient Development: Used in the research and synthesis of new generation herbicides, fungicides, and plant growth regulators.
• Catalyst Manufacturing: Serves as a fundamental building block for synthesizing specialized homogeneous and heterogeneous catalysts.
• Materials Science Research: Employed in the development of novel polymers, flame retardants, and electronic materials.
• Organic Synthesis Reagent: Acts as a phosphination agent for the introduction of phosphorus-containing functional groups into organic molecules.
• Ligand Library Construction: A vital starting material for combinatorial chemistry approaches to discover new phosphine ligands with tailored properties.

Basic Information

Product Name	tert-Butylchloroisopropylphosphine
CAS No.	29949-66-4
Molecular Formula	C7H16ClP
Molecular Weight	166.63 g/mol
Synonyms	Chloro(tert-butyl)isopropylphosphine; tert-Butyl(isopropyl)chlorophosphine; Isopropyl-tert-butylchlorophosphine; (1,1-Dimethylethyl)chloro(1-methylethyl)phosphine; t-Bu(i-Pr)PCl; tert-Butylchloro(isopropyl)phosphine; Chloro-tert-butyl-isopropyl-phosphine
EINECS	Contact for details

Quality Control

Our tert-Butylchloroisopropylphosphine is manufactured under stringent quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ³¹P) and GC analysis, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its moisture-sensitive (hygroscopic) and easily oxidized nature, this product must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Handle and dispense only in a controlled, moisture-free environment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 95.0%
³¹P NMR Purity	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.