Description

2-Bromo-4,5-Dimethyl-1,3-Thiazole is a versatile and highly functionalized heterocyclic building block, essential for advanced organic synthesis. Its core value lies in its reactive bromine substituent, which enables efficient cross-coupling reactions and further derivatization to create complex molecular architectures. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in the development of thiazole-containing bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the thiazole ring confers specific biological activity.
• Material Science Research: Acts as a monomer or functional additive in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and the development of chemical probes to study biological systems.
• Cross-Coupling Reactions: A valuable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Ligand Synthesis: Utilized in the preparation of novel nitrogen-sulfur (N,S) donor ligands for catalysis and coordination chemistry.

Basic Information

Product Name	2-Bromo-4,5-Dimethyl-1,3-Thiazole
CAS No.	29947-24-8
Molecular Formula	C5H6BrNS
Molecular Weight	192.08 g/mol
Synonyms	2-Bromo-4,5-dimethylthiazole; 4,5-Dimethyl-2-bromothiazole; Thiazole, 2-bromo-4,5-dimethyl-; 2-Brom-4,5-dimethylthiazol; 2-Bromo-4,5-dimethyl-δ4-thiazoline
EINECS	Contact for details

Quality Control

Our 2-Bromo-4,5-Dimethyl-1,3-Thiazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as identity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates, supporting our clients' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, handling and transfer should be minimized under direct light exposure.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.