Description

5-Pyrimidinethiol (8Ci,9Ci) is a sulfur-containing heterocyclic compound that serves as a versatile building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and functional materials. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical and agrochemical industries seeking to incorporate the pyrimidine-thiol moiety into target molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and kinase inhibitor drugs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Ligand for Metal Complexes: Acts as a chelating agent or ligand in the preparation of catalysts and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of organic semiconductors, conductive polymers, and other specialty materials.
• Biochemical Research: Useful as a modifying agent or probe in biochemical studies and proteomics research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	5-Pyrimidinethiol (8Ci,9Ci)
CAS No.	29878-64-6
Molecular Formula	C4H4N2S
Molecular Weight	112.15 g/mol
Synonyms	5-Mercaptopyrimidine; Pyrimidine-5-thiol; 5-Pyrimidinethiol; 5-Thiopyrimidine; 1H-Pyrimidine-5-thione; 5-Sulfanylpyrimidine; 29878-64-6 (CAS); 5-Pyrimidinol, thio-
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinethiol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to meet the stringent requirements of research and industrial applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.