Description

1-(4-Chloro-Phenyl)-Prop-2-Yn-1-Ol is a versatile organic building block featuring both a chloro-substituted aromatic ring and a propargylic alcohol functional group. This unique molecular structure makes it a valuable intermediate for synthesizing more complex molecules in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients. The compound's reactivity profile allows for selective modifications, enabling the construction of diverse chemical libraries.

Application

• Pharmaceutical Intermediate: Key synthon for the development of potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders or anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging the chloro-phenyl moiety for bioactivity.
• Organic Synthesis Building Block: Serves as a precursor for click chemistry reactions, Sonogashira couplings, and other palladium-catalyzed cross-couplings to create complex alkynes.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, or organic electronic materials due to its rigid aromatic and alkyne components.
• Chemical Biology Probes: Utilized in synthesizing molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	1-(4-Chloro-Phenyl)-Prop-2-Yn-1-Ol
CAS No.	29805-11-6
Molecular Formula	C9H7ClO
Molecular Weight	166.60 g/mol
Synonyms	4-Chlorophenyl propargyl alcohol; 1-(4-Chlorophenyl)-2-propyn-1-ol; 4-Chloro-α-(prop-2-yn-1-yl)benzyl alcohol; p-Chlorophenyl propargyl alcohol; 3-(4-Chlorophenyl)-3-hydroxy-1-propyne; 29805-11-6; 4-Chloro-α-propynylbenzyl alcohol
EINECS	Contact for details

Quality Control

Our 1-(4-Chloro-Phenyl)-Prop-2-Yn-1-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.