Description

3,5-Bis(Trifluoromethyl)Benzenediazonium is a highly reactive and versatile diazonium salt intermediate, essential for introducing the electron-deficient 3,5-bis(trifluoromethyl)phenyl group into complex molecular architectures. Its value lies in enabling efficient, site-specific functionalization via Sandmeyer and related coupling reactions, which are critical for synthesizing advanced materials and pharmaceuticals. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring the lipophilic and metabolically stable trifluoromethyl groups.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the bis(trifluoromethyl) moiety can improve biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in cross-coupling and other transition metal-catalyzed reactions.
• Material Science: Employed in the synthesis of monomers and polymers for advanced materials, such as fluorinated polyimides or liquid crystals, where the group imparts unique thermal and chemical resistance.
• Dye and Pigment Manufacturing: Acts as a diazo component in the production of high-performance, light-fast azo dyes and pigments.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for constructing complex aromatic and heteroaromatic systems via diazonium chemistry.

Basic Information

Product Name	3,5-Bis(Trifluoromethyl)Benzenediazonium
CAS No.	29684-26-2
Molecular Formula	C8H2F6N2+ X- (X = counterion, e.g., BF4-, Cl-)
Molecular Weight	Contact for details (varies by salt form)
Synonyms	3,5-Bis(trifluoromethyl)benzenediazonium salt; 3,5-Bis(trifluoromethyl)phenyldiazonium; Diazonium, [3,5-bis(trifluoromethyl)phenyl]-; α,α,α,α',α',α'-Hexafluoro-3,5-xylylenediazonium; 3,5-Di(trifluoromethyl)benzenediazonium; 1-Diazo-3,5-bis(trifluoromethyl)benzene
EINECS	Contact for details

Quality Control

Our 3,5-Bis(Trifluoromethyl)Benzenediazonium is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and titration, to ensure high purity and consistent reactivity. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under an inert atmosphere. This material is strictly light-sensitive and hygroscopic. Allow the container to reach ambient temperature in a desiccator before opening to minimize moisture uptake and thermal decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light beige powder or crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Anhydrous basis)
Water Content (KF)	≤ 2.0 %
Counterion Content	As specified (e.g., Tetrafluoroborate, Chloride)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.