Description

p-Tolylsulfonyldiazomethane is a versatile and highly reactive diazo compound used as a key reagent in organic synthesis. Its primary value lies in its ability to act as a methylene transfer agent, facilitating the synthesis of complex molecules under mild conditions. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials industries seeking efficient pathways for cyclopropanation and homologation reactions.

Application

• Pharmaceutical Intermediate Synthesis: Employed in the production of active pharmaceutical ingredients (APIs), particularly for the construction of strained ring systems.
• Agrochemical Research: Used in the development of novel pesticides and herbicides through cyclopropanation reactions.
• Polymer & Material Science: Acts as a cross-linking agent or modifier in the synthesis of specialty polymers and functional materials.
• Organic Methodology Development: A critical reagent in academic and industrial labs for developing new catalytic and stoichiometric C-H and C-C bond activation protocols.
• Fine Chemical Production: Utilized in the multistep synthesis of complex fragrances, dyes, and other high-value fine chemicals.

Basic Information

Product Name	p-Tolylsulfonyldiazomethane
CAS No.	1538-98-3
Molecular Formula	C8H8N2O2S
Molecular Weight	196.22 g/mol
Synonyms	Diazomethyl p-tolyl sulfone; (Diazo)(p-tolylsulfonyl)methane; p-Toluenesulfonyldiazomethane; Tosyldiazomethane; TsN2CH2; 4-Methylbenzenesulfonyldiazomethane; Diazomethyl tolyl sulfone; p-Tolylsulfonyldiazomethane
EINECS	Contact for details

Quality Control

Our p-Tolylsulfonyldiazomethane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is analyzed using advanced techniques including NMR, HPLC, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and easily oxidized nature, this material should be stored under an inert atmosphere (e.g., nitrogen or argon) at recommended temperatures between 2°C and 8°C. Keep the container in a cool, dry, and well-ventilated place, away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.