Description

2-(Chloroacetyl)Thiophene is a versatile and reactive organic building block, primarily used as a key intermediate in the synthesis of more complex molecules. Its value lies in the combination of the reactive chloroacetyl group and the thiophene heterocycle, enabling targeted chemical modifications. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing thiophene-based pharmacophores.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, leveraging its bioactivity for crop protection solutions.
• Material Science Research: Serves as a monomer or functionalization agent in the development of conductive polymers, organic semiconductors, and specialty polymers.
• Chemical Research & Development: A valuable reagent for organic synthesis, enabling the construction of complex heterocyclic compounds and facilitating novel reaction pathways.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of specialized dyes and pigments, particularly those requiring specific light-absorption properties.

Basic Information

Product Name	2-(Chloroacetyl)Thiophene
CAS No.	29683-77-0
Molecular Formula	C6H5ClOS
Molecular Weight	160.62 g/mol
Synonyms	2-Chloro-1-(2-thienyl)ethanone; 2-Chloroacetylthiophene; 1-(Thiophen-2-yl)-2-chloroethanone; α-Chloro-2-thenoylmethane; 2-Thenoyl chloride (ambiguous, but used); 2-Thienyl chloromethyl ketone; Chloromethyl 2-thienyl ketone; 2-(Chloroacetyl)-thiophene
EINECS	249-778-4

Quality Control

Our 2-(Chloroacetyl)Thiophene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.