Description

Methyl 2-(Diethylphosphono)Propanoate is a high-purity organophosphorus compound, specifically a phosphonate ester, serving as a critical building block in advanced organic synthesis. Its primary value lies in its role as a versatile Horner-Wadsworth-Emmons (HWE) reagent, enabling the efficient and stereoselective formation of carbon-carbon double bonds. This makes it an indispensable intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to synthesize complex molecules, including active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of α,β-unsaturated esters and other olefinic compounds used as building blocks for active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced herbicides, insecticides, and fungicides, leveraging its ability to form specific alkene geometries crucial for biological activity.
• Specialty Chemical Manufacturing: Employed in the synthesis of fine chemicals, flavors, fragrances, and functional materials requiring precise olefination steps.
• Academic & Industrial R&D: A fundamental reagent for method development and exploratory synthesis in organic chemistry laboratories worldwide.
• Polymer Chemistry: Potential use as a monomer or co-monomer precursor for creating polymers with specific phosphonate functionalities.

Basic Information

Product Name	Methyl 2-(Diethylphosphono)Propanoate
CAS No.	29668-62-0
Molecular Formula	C9H19O5P
Molecular Weight	238.22 g/mol
Synonyms	Diethyl (1-methoxy-1-oxopropan-2-yl)phosphonate; Methyl 2-(diethoxyphosphinyl)propanoate; 2-(Diethylphosphono)propionic Acid Methyl Ester; (Methoxycarbonyl)ethyldiethylphosphonate; Diethyl (2-methoxy-2-oxoethyl)(methyl)phosphonate; Phosphonic acid, P-[(1-methoxy-1-oxo-2-propanyl)]-, diethyl ester; Horner-Wadsworth-Emmons Reagent for methyl acrylate synthesis.
EINECS	Contact for details

Quality Control

Our Methyl 2-(Diethylphosphono)Propanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation (NMR, IR), to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.430 - 1.440
Density (g/mL, 20°C)	1.10 - 1.20

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.