Description

(+)-β-Hydrastine CAS NO 29617-43-4 is a high-purity, naturally occurring isoquinoline alkaloid, valued for its role as a key reference standard and active pharmaceutical ingredient (API) intermediate. Its significance lies in providing researchers and manufacturers with a reliable, well-characterized compound for analytical and developmental work. This product is essential for pharmaceutical R&D, quality control laboratories, and manufacturers focused on botanical extracts and alkaloid-based therapeutics.

Application

• Pharmaceutical Reference Standard: Primary use as a certified standard for the identification and quantification of hydrastine and related alkaloids in pharmaceutical testing and method validation.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a critical building block or precursor in the synthesis of more complex pharmaceutical compounds.
• Botanical Extract Analysis: Used in the quality control of goldenseal (*Hydrastis canadensis*) extracts to assay for hydrastine content, ensuring product potency and standardization.
• Biochemical Research: Employed in pharmacological and metabolic studies to investigate the biological activities of isoquinoline alkaloids.
• Analytical Method Development: A crucial component for developing and calibrating HPLC, LC-MS, and other chromatographic methods in analytical laboratories.

Basic Information

Product Name	(+)-β-Hydrastine
CAS No.	29617-43-4
Molecular Formula	C₂₁H₂₁NO₆
Molecular Weight	383.40 g/mol
Synonyms	(+)-β-Hydrastine; (S)-β-Hydrastine; β-Hydrastine; Hydrastine; 6,7-Dimethoxy-3-[(6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methyl]-1,3-benzodioxol-5-ol; 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-((5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)methyl)-, (S)-; Natural Hydrastine
EINECS	Contact for details

Quality Control

Our (+)-β-Hydrastine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.