Description

(1R,7Aβ,8S,αr)-Octahydro-6β,8-Dihydroxy-α,3Aβ,5α-Trimethyl-1α,4α,6-Metheno-1H-Indene-1-Acetic Acid is a high-purity, complex organic compound with a defined stereochemistry, making it a critical intermediate for advanced pharmaceutical synthesis. Its value lies in its role as a key chiral building block for the development of novel therapeutic agents, particularly in steroid and terpenoid-related research. This product is essential for R&D laboratories and production facilities in the pharmaceutical and fine chemical industries seeking reliable, high-quality intermediates for complex molecule construction.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially for steroidal or terpenoid-based drugs.
• Research & Development: Used in medicinal chemistry for the discovery and optimization of new chemical entities, leveraging its complex, polycyclic structure.
• Process Chemistry: Employed in route scouting and scale-up activities for the efficient production of target molecules in pilot plants and commercial manufacturing.
• Reference Standard: Can be utilized as an analytical standard for method development and quality control in laboratories to ensure product identity and purity.
• Fine Chemical Synthesis: Acts as a specialized building block for synthesizing complex natural product analogs and other high-value specialty chemicals.

Basic Information

Product Name	(1R,7Aβ,8S,αr)-Octahydro-6β,8-Dihydroxy-α,3Aβ,5α-Trimethyl-1α,4α,6-Metheno-1H-Indene-1-Acetic Acid
CAS No.	29598-40-1
Molecular Formula	C₁₇H₂₆O₄
Molecular Weight	294.39 g/mol
Synonyms	1H-Indene-1-acetic acid, octahydro-6,8-dihydroxy-α,3a,5-trimethyl-, (1R,3aS,5S,6R,7aR,8S)-rel-; 6β,8-Dihydroxy-α,3aβ,5α-trimethyl-1α,4α,6-metheno-1H-indene-1-acetic acid; 6β,8-Dihydroxy-α,3aβ,5α-trimethyl-1α,4α,6-methano-1H-indene-1-acetic acid; (1R,3aS,5S,6R,7aR,8S)-Octahydro-6,8-dihydroxy-α,3a,5-trimethyl-1,4-methano-1H-indene-1-acetic acid; A key intermediate for prostaglandin synthesis; Prostaglandin F2α intermediate.
EINECS	Contact for details

Quality Control

Our (1R,7Aβ,8S,αr)-Octahydro-6β,8-Dihydroxy-α,3Aβ,5α-Trimethyl-1α,4α,6-Metheno-1H-Indene-1-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and impurity profile analysis, to ensure it meets the high standards required for pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity, and specific tests are provided to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which could affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.