Description

Phenylthiohydantoin Methionine is a specialized derivative of methionine, a sulfur-containing amino acid, modified with a phenylthiohydantoin group. This compound is of significant value in biochemical research and analytical chemistry, particularly for protein sequencing and amino acid analysis. It is primarily utilized by research institutions, pharmaceutical development laboratories, and manufacturers of high-purity biochemical reagents.

Application

• Protein Sequencing Reagent: Used in the Edman degradation process for stepwise identification of amino acids in peptides and proteins.
• Amino Acid Analysis: Serves as a derivative for the chromatographic separation and detection of methionine residues.
• Biochemical Research: Employed in studies investigating protein structure, function, and post-translational modifications.
• Pharmaceutical Development: Used as a reference standard or intermediate in the synthesis and quality control of peptide-based drugs.
• Diagnostic Kit Manufacturing: A key component in kits designed for amino acid profiling and metabolic disorder diagnostics.
• Academic Research: Utilized in university and institutional labs for teaching and advanced research in biochemistry and molecular biology.

Basic Information

Product Name	Phenylthiohydantoin Methionine
CAS No.	29583-09-3
Molecular Formula	C12H14N2O2S2
Molecular Weight	282.38 g/mol
Synonyms	PTH-Methionine; 3-Phenyl-2-thiohydantoin Methionine; Methionine Phenylthiohydantoin; 2-Thio-5-(2-amino-2-carboxyethyl)-3-phenyl-4-imidazolidinone; Edman Degradation Product of Methionine; PTH-Met; (S)-2-Amino-4-(methylthio)butanoic acid phenylthiohydantoin derivative
EINECS	Contact for details

Quality Control

Our Phenylthiohydantoin Methionine is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and analytical applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.