Description

1-(4-Trifluoromethyl-Phenyl)-Cyclobutanol is a versatile fluorinated organic intermediate featuring a cyclobutanol ring system. This compound is valued for its unique structural motif, which is crucial for modulating the physicochemical properties of target molecules in advanced synthesis. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of new herbicides and fungicides, where the trifluoromethyl group can enhance bioavailability and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Precursor: Intermediate in the creation of specialty polymers and liquid crystals with tailored electronic or optical properties.
• Chemical Biology Probe Synthesis: Utilized to create molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	1-(4-Trifluoromethyl-Phenyl)-Cyclobutanol
CAS No.	29480-10-2
Molecular Formula	C11H11F3O
Molecular Weight	216.20 g/mol
Synonyms	1-[4-(Trifluoromethyl)phenyl]cyclobutanol; α-(4-Trifluoromethylphenyl)cyclobutylmethanol; 4-(1-Hydroxycyclobutyl)benzotrifluoride; (4-Trifluoromethylphenyl)cyclobutanol; Cyclobutanol, 1-[4-(trifluoromethyl)phenyl]-; 29480-10-2; 1-(4-Trifluoromethylphenyl)cyclobutanol
EINECS	Contact for details

Quality Control

Our 1-(4-Trifluoromethyl-Phenyl)-Cyclobutanol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.