Description

2'-Ethyl-12'-Hydroxy-5'α-(2-Methylpropyl)Ergotaman-3',6',18-Trione is a complex ergot alkaloid derivative with a specific, modified ergoline structure. This compound is of significant interest for advanced pharmaceutical research and development, particularly in the study of neurological and vascular receptor interactions. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers requiring high-purity, specialized intermediates for synthesis and biological evaluation.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel ergot-based therapeutic agents.
• Biochemical Research: Used as a reference standard or active compound in studies targeting serotonin (5-HT), dopamine, and adrenergic receptors.
• Neurology & Pharmacology R&D: Investigated for potential applications in modulating cerebral and peripheral blood flow, and for migraine research.
• Reference Standard: Employed in analytical laboratories for method development, calibration, and quality control of related substances.
• Preclinical Studies: Utilized in *in vitro* and *in vivo* models to assess efficacy, pharmacokinetics, and safety profiles.
• Process Chemistry: Acts as a starting material or intermediate for the scale-up and optimization of synthetic routes for complex molecules.

Basic Information

Product Name	2'-Ethyl-12'-Hydroxy-5'α-(2-Methylpropyl)Ergotaman-3',6',18-Trione
CAS No.	29475-05-6
Molecular Formula	C33H41N5O5
Molecular Weight	587.71 g/mol
Synonyms	2'-Ethyl-12'-hydroxy-5'α-(2-methylpropyl)ergotaman-3',6',18-trione; 5'α-(Isobutyl)-2'-ethyl-12'-hydroxyergotaman-3',6',18-trione; 12'-Hydroxy-2'-ethyl-5'α-(2-methylpropyl)ergotaman-3',6',18-trione; Ergotaman derivative; Dihydroergocristine-related compound; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2'-Ethyl-12'-Hydroxy-5'α-(2-Methylpropyl)Ergotaman-3',6',18-Trione is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.