Description

1H-Imidazo[4,5-B]Pyridine-2-Thiol is a versatile heterocyclic building block and key synthetic intermediate. This compound is valued for its unique fused-ring structure, which serves as a crucial scaffold in the development of advanced pharmaceuticals and agrochemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors, antiviral agents, and other biologically active molecules.
• Agrochemical Research: Used as a core structure for developing new fungicides, herbicides, and plant growth regulators.
• Material Science: Serves as a building block for organic semiconductors, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Synthesis: Employed in organic chemistry research for constructing complex heterocyclic systems and as a ligand in catalytic reactions.
• Bioconjugation & Probe Development: The thiol group allows for functionalization and conjugation, useful in creating biochemical probes and diagnostic agents.

Basic Information

Product Name	1H-Imidazo[4,5-B]Pyridine-2-Thiol
CAS No.	29448-81-5
Molecular Formula	C6H5N3S
Molecular Weight	151.19 g/mol
Synonyms	1H-Imidazo[4,5-b]pyridine-2-thiol; 2-Mercapto-1H-imidazo[4,5-b]pyridine; 2-Thioxo-2,3-dihydro-1H-imidazo[4,5-b]pyridine; Imidazo[4,5-b]pyridine-2-thiol; 1H-Imidazo[4,5-b]pyridine-2(3H)-thione; 29448-81-5; 2-Mercaptoimidazo[4,5-b]pyridine
EINECS	Contact for details

Quality Control

Our 1H-Imidazo[4,5-B]Pyridine-2-Thiol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.