Description

(2R)-2-Iodooctane is a high-purity chiral alkyl halide building block, specifically the (R)-enantiomer of 2-iodooctane. This compound is valued for its role in stereoselective synthesis, where it serves as a key electrophile for introducing the (R)-2-octyl moiety with high enantiomeric purity. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require enantiomerically pure intermediates for the development of active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in nucleoside and lipid-based drug development.
• Agrochemical Synthesis: Used in the preparation of chiral pesticides, herbicides, and plant growth regulators where specific stereochemistry is required for biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of chiral liquid crystals, polymers, and other functional materials with specific optical properties.
• Cross-Coupling Reactions: Acts as an electrophile in Negishi, Suzuki-Miyaura, and other palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Academic & R&D Laboratories: A standard reagent for methodological development in organic chemistry and stereochemistry education and research.

Basic Information

Item	Details
Product Name	(2R)-2-Iodooctane
CAS No.	29117-48-4
Molecular Formula	C8H17I
Molecular Weight	240.13 g/mol
Synonyms	(R)-2-Iodooctane; (R)-(-)-2-Iodooctane; (R)-2-Octyl iodide; (2R)-Octyl iodide; (+)-(R)-2-Iodooctane; 1-Iodo-2-methylheptane (stereospecific); (R)-1-Iodo-2-methylheptane; sec-Octyl iodide (R-enantiomer)
EINECS	Contact for details

Quality Control

Our (2R)-2-Iodooctane is manufactured under strict quality systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by Chiral HPLC or GC analysis to confirm enantiomeric excess (typically >98% ee), alongside standard identity and purity verification. Certificates of Analysis (COA) detailing specific results for assay, optical rotation, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to light and potential decomposition in strong acid/organic solvent environments, it should be kept in amber glass or opaque containers away from incompatible materials.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC/GC)	≥ 98.0%
Specific Optical Rotation [α]	Contact for details
Water Content (Karl Fischer)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.