Description

3,3-Bis(Hydroxymethyl)-2,3-Dihydro-4H-Thiochromen-4-One is a versatile sulfur-containing heterocyclic building block with a fused thiochromenone core. This compound matters as a key synthetic intermediate, offering reactive hydroxymethyl groups and a unique molecular scaffold for constructing complex molecules. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for applications in drug discovery, agrochemical synthesis, and advanced material science.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological or oncological pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators due to its bioactive thiochromenone structure.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic semiconductors, photoresponsive materials, and specialty polymers.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable building block for custom synthesis projects and scale-up production in fine chemical facilities.

Basic Information

Product Name	3,3-Bis(Hydroxymethyl)-2,3-Dihydro-4H-Thiochromen-4-One
CAS No.	29107-30-0
Molecular Formula	C11H12O3S
Molecular Weight	224.27 g/mol
Synonyms	3,3-Di(hydroxymethyl)-2,3-dihydro-4H-thiochromen-4-one; 2,3-Dihydro-3,3-bis(hydroxymethyl)-4H-thiochromen-4-one; 3,3-Bis(hydroxymethyl)-2,3-dihydro-4-thiochromenone; 3,3-Bis(hydroxymethyl)dihydrothiochromen-4-one; Thiochromenone diol derivative; 4H-Thiochromen-4-one, 2,3-dihydro-3,3-bis(hydroxymethyl)-; 29107-30-0
EINECS	Contact for details

Quality Control

Our 3,3-Bis(Hydroxymethyl)-2,3-Dihydro-4H-Thiochromen-4-One is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.